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Year Number of Results
2001 1
2005 1
2008 1
2009 2
2010 1
2012 2
2013 1
2014 2
2015 1
2016 2
2018 1
2019 1
2020 2
2021 1
2022 1
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18 results

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Page 1
NCAPG promotes the oncogenesis and progression of non-small cell lung cancer cells through upregulating LGALS1 expression.
Sun H, Zhang H, Yan Y, Li Y, Che G, Zhou C, Nicot C, Ma H. Sun H, et al. Mol Cancer. 2022 Feb 18;21(1):55. doi: 10.1186/s12943-022-01533-9. Mol Cancer. 2022. PMID: 35180865 Free PMC article.
Mechanistically, the function of NCAPG in promoting initiation and progression of NSCLC was closely related to LGALS1, which was also upregulated in NSCLC and might interact directly with NCAPG. ...
Mechanistically, the function of NCAPG in promoting initiation and progression of NSCLC was closely related to LGALS1, which was also …
Galectin-1 promotes lung cancer progression and chemoresistance by upregulating p38 MAPK, ERK, and cyclooxygenase-2.
Chung LY, Tang SJ, Sun GH, Chou TY, Yeh TS, Yu SL, Sun KH. Chung LY, et al. Clin Cancer Res. 2012 Aug 1;18(15):4037-47. doi: 10.1158/1078-0432.CCR-11-3348. Epub 2012 Jun 13. Clin Cancer Res. 2012. PMID: 22696230
PURPOSE: This study is aimed at investigating the role and novel molecular mechanisms of galectin-1 in lung cancer progression. EXPERIMENTAL DESIGN: The role of galectin-1 in lung cancer progression was evaluated both in vitro and in vivo by short hair …
PURPOSE: This study is aimed at investigating the role and novel molecular mechanisms of galectin-1 in lung cancer progression …
Relationship between podoplanin-expressing cancer-associated fibroblasts and the immune microenvironment of early lung squamous cell carcinoma.
Suzuki J, Aokage K, Neri S, Sakai T, Hashimoto H, Su Y, Yamazaki S, Nakamura H, Tane K, Miyoshi T, Sugano M, Kojima M, Fujii S, Kuwata T, Ochiai A, Tsuboi M, Ishii G. Suzuki J, et al. Lung Cancer. 2021 Mar;153:1-10. doi: 10.1016/j.lungcan.2020.12.020. Epub 2020 Dec 24. Lung Cancer. 2021. PMID: 33429158
RESULTS: Analysis of TCGA database revealed that the PDPN-high group exhibited significantly higher expression of interleukin (IL)-1A, IL-1B, IL-6, IL-10, monocyte chemoattractant protein-1 (CCL2), colony stimulating factor 1 (CSF1), fibroblast growth factor 2 (FGF2), galectin …
RESULTS: Analysis of TCGA database revealed that the PDPN-high group exhibited significantly higher expression of interleukin (IL)-1A, IL-1B …
Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin alpha6beta4 and Notch1/Jagged2 signaling pathway.
Hsu YL, Wu CY, Hung JY, Lin YS, Huang MS, Kuo PL. Hsu YL, et al. Carcinogenesis. 2013 Jun;34(6):1370-81. doi: 10.1093/carcin/bgt040. Epub 2013 Feb 6. Carcinogenesis. 2013. PMID: 23389289
However, the functional role of galectin-1 in lung cancer per se remains unknown. We demonstrate that ectopic expression of galectin-1 in a low-metastatic CL1-0 lung cancer cell line promotes its migration, invasion and epithelial-mesenchymal transitio …
However, the functional role of galectin-1 in lung cancer per se remains unknown. We demonstrate that ectopic expression of …
Lung cancer-derived galectin-1 enhances tumorigenic potentiation of tumor-associated dendritic cells by expressing heparin-binding EGF-like growth factor.
Kuo PL, Huang MS, Cheng DE, Hung JY, Yang CJ, Chou SH. Kuo PL, et al. J Biol Chem. 2012 Mar 23;287(13):9753-9764. doi: 10.1074/jbc.M111.321190. Epub 2012 Jan 30. J Biol Chem. 2012. PMID: 22291012 Free PMC article.
This study is the first to indicate that lung cancer-derived galectin-1 secretion is responsible for stimulating tumor-associated dendritic cells (TADCs) production of mature heparin-binding EGF-like growth factor (HB-EGF), which, in turn, increases cancer progressi …
This study is the first to indicate that lung cancer-derived galectin-1 secretion is responsible for stimulating tumor-associa …
Galectin-1 is overexpressed in CD133+ human lung adenocarcinoma cells and promotes their growth and invasiveness.
Zhou X, Li D, Wang X, Zhang B, Zhu H, Zhao J. Zhou X, et al. Oncotarget. 2015 Feb 20;6(5):3111-22. doi: 10.18632/oncotarget.3076. Oncotarget. 2015. PMID: 25605013 Free PMC article.
We overexpressed galectin-1 in CD133- cancer cells and downregulated it in CSCs. We found that overexpression of galectin-1 promoted invasiveness of CD133- cells, while knockdown of galectin-1 suppressed proliferation, colony formation an …
We overexpressed galectin-1 in CD133- cancer cells and downregulated it in CSCs. We found that overexpression of galectin …
Lung cancer-derived galectin-1 contributes to cancer associated fibroblast-mediated cancer progression and immune suppression through TDO2/kynurenine axis.
Hsu YL, Hung JY, Chiang SY, Jian SF, Wu CY, Lin YS, Tsai YM, Chou SH, Tsai MJ, Kuo PL. Hsu YL, et al. Oncotarget. 2016 May 10;7(19):27584-98. doi: 10.18632/oncotarget.8488. Oncotarget. 2016. PMID: 27050278 Free PMC article.
Inhibition of the AKT/CREB pathway prevents cancer proliferation, while inhibition of the AKT/ WNK1 reverted epithelial-to-mesenchymal transition and cancer migration induced by kynurenine. Moreover, we also demonstrate that lung cancer-derived galectin-1 contribute …
Inhibition of the AKT/CREB pathway prevents cancer proliferation, while inhibition of the AKT/ WNK1 reverted epithelial-to-mesenchymal trans …
HDGF enhances VEGF‑dependent angiogenesis and FGF‑2 is a VEGF‑independent angiogenic factor in non‑small cell lung cancer.
Eguchi R, Wakabayashi I. Eguchi R, et al. Oncol Rep. 2020 Jul;44(1):14-28. doi: 10.3892/or.2020.7580. Epub 2020 Apr 9. Oncol Rep. 2020. PMID: 32319650 Free PMC article.
Among the identified proteins, interleukin-8 (IL-8), macrophage migration inhibitory factor (MIF), galectin-1, midkine (MK), IL-18, galectin-3, VEGF-A, hepatoma-derived growth factor (HDGF), osteopontin (OPN), connective tissue growth factor (CTGF) and granulin (GRN …
Among the identified proteins, interleukin-8 (IL-8), macrophage migration inhibitory factor (MIF), galectin-1, midkine (MK), I …
Clinical relevance of galectin-1 expression in non-small cell lung cancer patients.
Carlini MJ, Roitman P, Nuñez M, Pallotta MG, Boggio G, Smith D, Salatino M, Joffé ED, Rabinovich GA, Puricelli LI. Carlini MJ, et al. Lung Cancer. 2014 Apr;84(1):73-8. doi: 10.1016/j.lungcan.2014.01.016. Epub 2014 Jan 28. Lung Cancer. 2014. PMID: 24560493
BACKGROUND: Identification of biomarkers in lung cancer, a leading cause of cancer-related mortality, has a meaningful clinical relevance in the quest of novel prognostic factors and therapeutic targets. The glycan-binding protein galectin-1 (Gal-1) modulates tumor …
BACKGROUND: Identification of biomarkers in lung cancer, a leading cause of cancer-related mortality, has a meaningful clinical relevance in …
18 results